Study: Lactobacillus Reuteri DSM 17938 seems to reduce colic

Von Natur.wiki Autoren-Team

In dieser Studie geht es um die Wirkung von Lactobacillus reuteri DSM 17938 auf kolikartige Säuglinge. Es handelt sich um eine randomisierte, doppelblinde, placebokontrollierte Studie, bei der fünfzig ausschließlich gestillte Säuglinge entweder Lactobacillus reuteri DSM 17938 oder ein Placebo erhielten. Die Ergebnisse zeigten, dass die Einnahme von Lactobacillus reuteri zu einer Verkürzung der täglichen Schreizeit führte und eine Veränderung der Stuhlmikroflora bewirkte. Die Autoren geben an, dass Probiotika wie Lactobacillus reuteri die Darmmotilität und -funktion verbessern könnten. Stillen wurde ebenfalls als wirksame Behandlungsmethode genannt, da es das mikrobielle Milieu im Darm verbessert. Die Studie schlägt vor, dass weitere Forschung notwendig …
This study deals with the effect of Lactobacillus Reuteri DSM 17938 on colic -like infants. It is a randomized, double -blind, placebo -controlled study, in which fifty infants only received breastfed infants either Lactobacillus Reuteri DSM 17938 or a placebo. The results showed that the intake of Lactobacillus Reuteri led to a shortening of the daily screaming time and caused a change in the chair microflora. The authors state that probiotics such as Lactobacillus Reuteri could improve the intestinal and function. Breastfeeding was also mentioned as an effective treatment method because it improves the microbial milieu in the intestine. The study suggests that further research is necessary ... (Symbolbild/natur.wiki)

This study deals with the effect of Lactobacillus Reuteri DSM 17938 on colic -like infants. It is a randomized, double -blind, placebo -controlled study, in which fifty infants only received breastfed infants either Lactobacillus Reuteri DSM 17938 or a placebo. The results showed that the intake of Lactobacillus Reuteri led to a shortening of the daily screaming time and caused a change in the chair microflora. The authors state that probiotics such as Lactobacillus Reuteri could improve the intestinal and function. Breastfeeding was also mentioned as an effective treatment method because it improves the microbial milieu in the intestine. The study suggests that further research is necessary to examine the use of other probiotic tribes in the treatment of colic.

Details of the study:

Reference

Savino f, Cordisco L, Tarasco V, et al. Lactobacillus Reuteri DSM 17938 in childlike colic: a randomized, double -blind, placebo -controlled study. pediatrics. 2010; 126 (3): E526-E533.

Design

randomized, double blind, placebo -controlled study

participant

fifty -exclusively breastfed colic -like infants

study medication and dosage

The infants received both l. Reuteri DSM 17938 (10 (8) KBE) or placebo daily for 3 weeks. Parent questionnaires monitored the daily screaming time and the side effects. For microbiological analysis, stool samples were taken.

most important knowledge

who take l. Reuteri experienced a significant shortening of the daily screaming period. The chair microbiology showed an increase in lactobacilli and a decrease in lactobacilli Escherichia coli in the treatment group. l. Reuteri was well tolerated and no side effects were found.

Breastfeeding can be an equally effective treatment because it improves the microbial milieu in the intestine.

effects on practice

In naturopathy, it is known that probiotics effectively combat many gastrointestinal complaints, also as monotherapy. The same authors carried out a similar study in 2007, in which it was found that a related probiotic tribe, l. Reuteri ATCC 77530 led to a reduction in colic symptoms in 95 % of the treatment group compared to 7 % in the control group. 1 Critics of this study point out that it was not stored and the control persons were treated with Simethicon. Strength and meaning. The mechanisms behind the advantages of probiotics are not fully clarified. However, there are some hints in the literature: Savino and colleagues indicate that probiotics could improve the intestinal engineism and function 3 and visceral pain. 4.5 In addition, other studies have shown that in infants with colic there is a changed stool microflora and that an increased calprotect insert in these children is determined. 6 Interestingly, Calprotectin is a marker for intestinal inflammation and possibly an increased intestinal permeability 7.8 and can serve as a predictor for irrelevant disease in later life.

Breastfeeding can be an equally effective treatment because it improves the microbial milieu in the intestine. This explains why a review of 79 articles shows that breastfed babies in later life have a lower risk of developing a irritable bowel disease. 9 At the moment there is no general consensus about which probiotic tribes for the treatment of colic are most effective. Other tribes that have proven to be effective in colic include: bifidobacterium lactis and streptococcus thermophilus. 10 It is very likely that other tribes also benefit from what further research in this area justifies.

  1. Savino f, Pelle E, Palumeri E, Oggero R, Miniero R. Lactobacillus Reuteri (American Type Culture Collection Stamm 77530) Versus Simethicon in the treatment of child colic: a prospective randomized study. Pädiatrie . 2007; 119: E124-30.
  2. Cabana Md. Lactobacillus Reuteri DSM 17938 seems to effectively shorten the screaming time in colic. j Pädiatr . 2011 March; 158 (3): 516-7.
  3. Indrio F, Riezzo G, Raimondi f, et al. The effects of probiotics on food tolerance, the stool habits and gastrointestinal engines in premature babies. j Pädiatr . 2008; 152 (6): 801–806
  4. Kunze WA, MAO YK, Wang B, et al. Lactobacillus Reuteri increases the excitability of AH neurons in the large intestine by inhibiting the calcium-dependent potassium channel opening. J Cell Mol Med . 2009; 13 (8b): 2261–2270
  5. Wang B, Mao YK, Diorio C, et al. The intake of Lactobacillus Reuteri and the blockade of the IK (CA) channel have similar effects on colon motility and myentric neurons of rats. neurogastroenterol Motil . 2010; 22 (1): 98-107, E33
  6. rhoads jm, fathere ny, norori j, liu y, lucke jf, tyson je, ferris mj. Changed fecal microflora and increased faecal calprotectin in infants with colic. j Pädiatr . 2009 Dec; 155 (6): 823-828.e1.
  7. Røseth AG, Schmidt PN, Fagerhol Mk. Correlation between the faecal excretion of indium-111-marked granulocytes and calprotectin, a granulocyte marker protein, in patients with inflammatory bowel diseases. scand j Gastroenterol . 1999; 34: 50-4.
  8. Berstad A, Arslan G, Folvik G. Connection between intestinal permeability and calprotectin concentration in the intestinal fluid. scand j Gastroenterol . 2000; 35: 64-9.
  9. Barclay AR, Russell RK, Wilson ML, Gilmour Wh, Satsangi J, Wilson Dc. Systematic overview: The role of breastfeeding in the development of inflammatory bowel diseases in children. j Pädiatr . 2009 Sep; 155 (3): 421-6.
  10. Saavedra JM, Abi-Hanna A, Moore N, Yolken Rh. Long -term consumption of infant beginnings with living probiotic bacteria: tolerability and security. am j clin nutr . 2004 Feb; 79 (2): 261-7.