Dissolve mediators & inflammation

Dissolve mediators & inflammation

mediators & inflammation

by Gene Bruno, MS, MHS, RH (AHG)

Huntington College for Health Sciences

inflammation are an important mechanism that is involved in many human diseases. Since longer inflammation for the host is harmful, higher organisms have developed protective mechanisms to ensure the dissolution of the inflammatory reaction to a limited and specific period and space. Once intended as a purely passive process of dilution of inflammation, the resolution is now regarded as a highly orchestrated process that is coordinated by a complex regulatory network of cells and mediators. 1

mediators dissolve
Among the molecules that facilitate the resolution are resolvine, protectine and maresine, which are generated from omega-3 fatty acids, the lipid mediators that have attracted the most attention. These endogenous anti -inflammatory and resolving mediators counteract the effects of inflammatory -promoting signal systems and act as "brake signals" of the continued vicious circle, which leads to an unstoppable inflammation.

In fact, the same inflammatory factors that initially trigger the inflammatory reaction also signal the end of the inflammation by stimulating the biosynthesis of inflammatory mediators. Resolvine, protectine and maresine have been shown to reduce respiratory inflammation, skin inflammation, colitis, arthritis and postoperative pain. Studies have shown that these mediators increase over time during the inflammatory process.2-4

dha
While all omega-3 fatty acids can contribute to the formation of resolvins, docosapentaenic acid (dpa), an intermediate product in the biosynthesis of DHA from EPA, is a particularly effective forerunner of four different resolvins, namely RVT1 (2), RVT3 (3) and RVT4.5 Nevertheless, dpa is not always in Omega-3 fatty acid products found. However, it can be found in some liver trans products.

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Professor Gene Bruno, MS, MHS, The provost for Huntington College for Health Sciences, is a nutritionist, herbalist, author and educator. For more than 37 years, he has trained and trained natural product retailers and medical staff, researched and formulated natural products for dozens of food supplements and formulated articles on nutrition, herbal medicine, nutrotquional agents and integrative health issues for trade and consumers. It can be reached at gbruno@hchs.edu.

• brake signals
• dha
• Dilution of the inflammation
• docosapentaenic acid
• data protection
• epa
• human diseases
• inflammation
• inflammatory reaction
• lipid mediators
• mare animals
• mechanism
• molecules
• omega-3 fatty acids
• Prof. Gene Bruno Blog
• extended inflammation
• resolving mediators
• protects
• dissolves to

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