Three little pain studies with CBD
Three little pain studies with CBD
Three small pain studies with CBD
by Prof. Gene Bruno, MS, MHS, RH (AHG)
Huntington University of Health Sciences
cannabidiol (CBD) is used to a large extent for a variety of diseases, including pain therapy. In the following you will find summaries of three published studies on the use of CBD in pain therapy for small, unique population groups
pain in kidney transplants
Since chronic pain in kidney transplant patients represent a major therapeutic problem, a study1 was carried out to evaluate the effect, security and possible drug interactions of CBD in chronic pain in seven kidney transplant patients between the ages of 58 and 75. The dose was increased from 50 to 150 mg twice a day for three weeks. The CBD beginning dose was 100 mg/day, and two patients needed a dose reduction. The results were that two patients had a complete improvement in the pain, four had a partial reaction in the first 15 days and did not change in the event of a change. The researchers stated that CBD was well tolerated and that there were no serious side effects.
epidermolysis bulllosa pain
epidermolysis bulllosa is a rare bubble -forming skin disease, the treatment of which is difficult, since skin breaks and repeated wound healing cause itching, pain, limited mobility and recurring infections. In an observation study2, three patients with epidermolysis bullosa initiated the topical CBD application themselves. The results were that a patient was completely weaned by oral opioid analgesics, and all three reported about faster wound healing, less bladder formation and relief of the pain when using CBD.
pain caused by HPV vaccine
An anecdotal, retrospective, open observation study with "Compassionate-Feuse" was vaccinated with sublingual CBD-rich hemp drops in eight women (age 12-24 years) with undesirable drug effects (including pain) according to human papilloma virus (HPV)). The dose was 25 mg/kg per day, supplemented by 2-5 mg/ml CBD once a week, a maximum dose of 150 mg/ml CBD per day was reached over a period of three months. The quality of life of the patients was evaluated with the short-form health questionnaire on medical results (SF-36). The results showed significant advantages in terms of physical component (p <0.02), vitality (p <0.03) and social role function (p <0.02) after treatment. According to the SF-36 assessment, the administration of hemp oil also significantly reduced body pain.
FAZIT
Research on the use of CBD in the treatment of different pain syndromes is underway. In the meantime, initial investigations indicate that CBD could be useful in the treatment of pain related to kidney transplants, epidermolysis bullosa and HPV vaccine.
references:
1 cuñetti l, Manzo L, Peyraube R, Arnaiz J, Curi L, Orihuela S. Chronic pain treatment with cannabidiol in kidney transplant patients in Uruguay. Transplantation procedure 2018 March; 50 (2): 461-464.
2 Chelliah MP, Zinn Z, Khuu P, Teng JMC. Self -initiated use of topical cannabidiol oil in epidermolysis bullosa. Pediatrician Dermatol. 2018 July; 35 (4): E224-E227.
3 Palmieri B, Laurino C, Vadalà M. Short-term effectiveness of CBD-enriched hemp oil in girls with dys autonomous syndrome after vaccination with human papillomavirus. Isr Med Assoc J. 2017 Feb; 19 (2): 79-84.
Professor Gene Bruno, MS, MHS, The provost for Huntington College for Health Sciences, is a nutritionist, herbalist, author and educator. For more than 37 years, he has trained and trained natural product retailers and medical staff, researched and formulated natural products for dozens of food supplements and formulated articles on nutrition, herbal medicine, nutrotquional agents and integrative health issues for trade and consumers. It can be reached at gbruno@hchs.edu.
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