Study: vitamin D and depression

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In der Studie geht es darum, den Zusammenhang zwischen Vitamin-D-Konzentrationen im Serum und Depressionen bei jungen Erwachsenen in den USA zu untersuchen. Es handelt sich um eine große Bevölkerungsquerschnittsstudie, bei der die Vitamin-D-Konzentrationen im Serum gemessen und eine diagnostische Beurteilung einer Depression durchgeführt wurden. Die Autoren stellen einen direkten Zusammenhang zwischen Vitamin-D-Mangel und der Depressionsvariable fest. Es wird eine hohe Prävalenz suboptimaler Vitamin-D-Serumkonzentrationen bei bestimmten Gruppen festgestellt. Die Studie legt nahe, dass Vitamin D eine Rolle bei der Regulation von Neurotransmittern und der oxidativen Aktivität spielen könnte und dass Ärzte den individuellen Vitamin-D-Spiegel bei Patienten mit Depressionen beurteilen und entsprechend …
The study is about examining the connection between vitamin D concentrations in serum and depression in young adults in the USA. It is a large population cross-section study in which the vitamin D concentrations in the serum were measured and a diagnostic assessment of depression was carried out. The authors determine a direct connection between vitamin D deficiency and the depression variable. A high prevalence of suboptimal vitamin D serum concentrations is determined for certain groups. The study suggests that vitamin D could play a role in regulation neurotransmitters and oxidative activity and that doctors assess individual vitamin D levels in patients with depression and ... (Symbolbild/natur.wiki)

The study is about examining the connection between vitamin D concentrations in serum and depression in young adults in the USA. It is a large population cross-section study in which the vitamin D concentrations in the serum were measured and a diagnostic assessment of depression was carried out. The authors determine a direct connection between vitamin D deficiency and the depression variable. A high prevalence of suboptimal vitamin D serum concentrations is determined for certain groups. The study suggests that vitamin D could play a role in regulating neurotransmitters and oxidative activity and that doctors should assess the individual vitamin D level in patients with depression and treat them accordingly.

Details of the study:

reference

ganji v, Milone C, Cody MM, McCarty F, Wang Yt. Serum vitamin D concentrations are related to depression in young adults in the United States: the third national health and nutritional examination survey. int Arch me d. 2010; 3: 29.

design

This is a large population cross -section study. The study sample initially included 18,875 participants. The final sample size comprised 7,970 US, non-institutionalized civilian participants between the ages of 15 and 39 after the exclusion of pregnancy and breastfeeding. The vitamin D concentrations in the serum were measured and a diagnostic assessment of depression based on the Diagnostic Interview Schedule (DIS).

most important findings

The authors found a direct connection between vitamin D deficiency and the depression variable. The prevalence of suboptimal vitamin D serum concentrations (<75 NMOL/L) was about 50 %, and 20 % were below 50 Nmol/l.

A higher prevalence was found in women, non-Hispanic blacks, people with a higher body mass index, people with less income, city residents and people living in the south.

restrictions

The data acquisition took place in different months - summer in the northeast and middle west and winter in the south. This could significantly change the prevalence of the determined vitamin D deficiency.

Effects on the practice

The role of vitamin D in depression is not fully clarified. It could play a role in regulating neurotransmitters and oxidative activity in connection with the glutathione metabolism. 1 This large population study observed a significantly greater probability of depression in people with vitamin D deficiency. Even if future research work has to be carried out to assess the causality, doctors can still assess the individual vitamin D level in patients with depression and treat them accordingly.