Study: urban air pollution and insulin resistance, type 2 diabetes and obesity

doctors have to start paying attention to the countless harmful effects of simple inhaling of air in all metropolitan areas.

Insulin sensitivity was assessed with an insulin-modified frequently carried out intravenous glucose tolerance test with 13 samples. The data from this test provided an evaluation for the full body insulin sensitivity (Si), the acute insulin reaction to glucose (Airg) and the evaluation of the beta zell function (disposition index [di])). The body mass index (BMI) was also measured during the entire study.

primary result measurements

one of the primary result measurements:

• full body insulin sensitivity
• acute insulin reaction to glucose
• beta cell function
• obesitas

important knowledge

Both PM2.5 and No _{2 were associated with a statistically significant reduction in insulin sensitivity; No 2 was associated with a statistically significant decrease in beta -tale function. Both PM2.5 and No 2 were connected to a statistically significant increase in the BMI.}

practice implications

lifestyle approaches to prevention and treatment of insulin resistance, metabolic syndrome and T2DM typically focus on nutrition and movement in order to reduce the number of calories absorbed and increase the number of calories burned. Nevertheless, a number of environmental pollutants were clearly associated with an increased risk for T2DM, including persistent organic pollutants and arsenic.

In the past ten years, articles have started to connect vehicle gases - the air pollution of the surroundings, which is generally increased in all urban areas around the world - with metabolic anomalies. In the past 7 years, several studies have shown that adults and adolescents who are exposed to higher concentrations of nitrogen monoxide, no, 2 , and PM2.5 had higher installments of T2DM. Three studies have shown that children and adults with increased exposure to vehicle gases had a higher calculated insulin resistance (using the homeostatic model evaluation of insulin resistance [HOMA-IR]). ^{1-3 Da Homa-I-I-IR results are not always confirmed by glucose tolerance tests.}

This new study contributes to the evidence that urban air pollution is associated with insulin resistance, beta zell function and obesity. Doctors have to start paying attention to the countless harmful effects of simple inhaling of air in all metropolitan areas. Air purification devices for at home that push air through a series of filters to remove particles up to a size of 1 micron should be on the list of "must-havees" for all patients, right next to water filters, organic variants of the "dirty dozen" (most toxic fruits and vegetables) and movement.