Study: Food lignees improve survival in breast cancer
Study: Food lignees improve survival in breast cancer
The study presented is about examining the connection between the inclusion of Lignan about food and survival in women with breast cancer. Data from 1,122 women aged 35-79 were analyzed in which breast cancer was diagnosed between 1996 and 2001. The eating habits were evaluated using a questionnaire and epidemiological interviews and the lign absorption was calculated on the basis of published data for the food composition. The results show that postmenopausal women who consumed most of the lignans had a lower risk of dying from breast cancer. The study therefore proposes to actively promote the consumption of lignan -containing foods, especially in women after menopause.
Reference
McCann SE, Thompson LU, Nie J, et al. Food intake of Lignan in relation to survival in women with breast cancer: the Western New York Exposures and Breast Cancer (Web) Study. treatment of breast cancer. 2010; 122 (1): 229-235.
Design
Statistical evaluation of the data collected on the nutritional habits of women with breast cancer. The diet in the 12–24 months before the diagnosis was assessed with an extensive questionnaire for the frequency of food and disruptive factors were determined using an epidemiological interview and abstract clinical data. The lign absorption was calculated on the basis of published data on the food composition.
Participant: 1,122 women aged 35-79 years, in which breast cancer was diagnosed between 1996 and 2001. The data was collected as part of a study on lifelong alcohol consumption and breast cancer (web study).
Study methodology
The connection between the absorption of Lignan about food and survival was analyzed. The vital status was followed by the end of 2006. Extensive food questionnaires were used to follow the diet one to two years before the initial diagnosis. The lign absorption was calculated using current tables for food composition. Hazard Ratios (HR) were calculated for the absorption of Lignan on food with total mortality and breast cancer mortality.
result measure
vital status (alive or deceased)
most important knowledge
postmenopausal women who consumed most of the lignans had a significantly lower risk of dying from any cause and especially breast cancer than women who consumed only small amounts of food -containing food. When comparing the upper and lower quarters of the lign absorption, there was a reduction in the total mortality by 51 % (HR 0.49, 95 % KI: 0.26–0.91) for those who consumed the higher amounts of lignan. In these women, the risk of dying from breast cancer was 71 % lower (HR 0.29, 95 %-KI: 0.11–0.76). A high absorption of dried beans (HR 0.61, 95 %-KI: 0.36–1.03) could also have reduced the overall mortality and breast cancer death risk (HR 0.53, 95 %KI: 0.24–1.14), although these numbers do not achieve statistical significance.
effects on practice
This is the first work that examines the connection between lign absorption before breast cancer diagnosis and risk of death. These results suggest that we should actively promote the consumption of lignan -containing foods, especially for women after menopause.
However, if the absorption of some specific foods with a high level of lign content in the diet can only reduce breast cancer mortality by a fraction of the amount shown in this data, it is definitely worth a try.
Since the data of the Women’s Healthy Eating and Living (Whel) study were published, which indicate that a diet with lots of fruit and vegetables and little fat has little influence on the chest cancer forecast, researchers and clinicians have tried to define what "good" is "The diet should be intended for patients, in which there is a breast cancer or with breast cancer was diagnosed. ” 1 The promotion of a high lign absorption is easier said than done because only a few patients understand what a lignan is and what food it contains. For the women participating in this study, the main sources of food for Lignane Darkes bread, peaches, coffee, broccoli and winter pumpkin were. Other foods are far better sources. While coffee can contain up to 30 µg/100 ml, 100 grams of kale contain several thousand µg lignanes. Flax seeds contain over 300,000 µg/100 grams and sesame seeds almost 40,000 µg/100 grams.
In McCann's study, the average lign recording was 244 µg/day. In postmenopausal women, eating <155 µg/day resulted in an HR for the total and breast cancer mortality of 1.00. As consumption increased, the heart rate fell; The slightest risk of death was found in women who consumed more than 318 µg per day. Reaching these values should be relatively easy to reach. Doctors and patients may find a useful table for the lignant content of food at: www.dietaryfiberfood.com/lignan.php This study was not a clinical study; Maybe that's why these results seem almost too beautiful to be true. However, if the absorption of some specific foods with a high lign extension in the diet can only reduce breast cancer mortality by a fraction of the amount shown in this data, it is definitely worth a try. For further research on integrative oncology, click here here.
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