Study: air pollution worsens diabetes

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In this study with cross -sectional data from Italy, the researchers discovered a direct connection between the fine dust content in the air and the increase in the hospital admissions of diabetics over 45. This paper is part of our special environmental medicine. Read the entire issue below. Reference Solimini AG, d’Addario M, Villari P. Ecological context between diabetes hospital admissions and fine dust in Italian provinces. BMC public health. 2015; 15 (1): 708. Design cross-sectional data from Italian institutional and regional databases were aggregated from 2008 to 2010 in order to determine correlations between hospital arrests with diabetes and fine dust (PM2.5) values, whereby common risk factors and socio-economic factors were adapted. Data The data includes 48 Italian ...
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In this study with cross -sectional data from Italy, the researchers discovered a direct connection between the fine dust content in the air and the increase in the hospital admissions of diabetics over 45 years.

This paper is part of our special environmental medicine. Read the entire issue below.

Reference

Solimini AG, d’Addario M, Villari P. Ecological context between diabetes hospital admissions and fine dust in Italian provinces. BMC Public health. 2015; 15 (1): 708.

Design

cross-sectional data were aggregated from Italian and regional databases from 2008 to 2010 in order to determine correlations between hospital arrangements with diabetes and fine dust (PM2.5) values, whereby common risk factors and socio-economic factors were adapted.

data

The data comprises 48 Italian provinces with a population of more than 34 million inhabitants (60 % of the total Italian population). The average fine dust values ​​up to a size of 2.5 micrometers (PM2.5) between 2008 and 2010 were between 11 μg/m3 3 to 32 μg/m 3 with an average of 20.1 μg/m 3 The layoffs from diabetes hospitals in patients over 45 years were between 4.6 and 66.9 per 10,000 with an average of 16.2; The range for men was between 8.4 and 83.8 per 10,000 with an average of 23.4.

particle measurements

The annual PM2.5 values ​​of Italian cities have been preserved in hourly measurements of surveillance stations that belong to regional networks. The period and the measurement stations were chosen to match the hospital development data at the state level.

important knowledge

Diabetes hospitalization increased with increasing annual PM2.5 concentrations, with an increase of 3.5 %(1.3 %–5.6 %) in men and 4.0 %(1.5 %–6.4 %) in women per µg/m3 pm2.5 increase.

practice implications

This paper suggests that control of exposure to air pollution can reduce the occurrence of diabetes and complications (especially hospital stays) for diabetics. This is a connection that only a few practitioners think of when they work with this patient group. Although we are aware that what and how much we eat, influence the weight, metabolic syndrome and diabetes, these two factors do not take into account how well we process calories. Increasing evidence show that excessive exposure to environmental toxins from all sources can negatively influence the metabolic pathways of humans.
more and more evidence show that excessive exposure to environmental toxins from all sources can negatively influence the metabolic pathways of humans.
At least 5 cohort studies have been looking for a connection between air pollution and type 2 diabetes. Krämer reported in 2010 that traffic-related air pollution was associated with type 2 diabetes in older women in the industrialized Ruhr area in Germany. 1 A study from 2013 that examined a cohort of more than 60,000 people in Ontario, Canada, reported an increase in diabetes incidence by 11 % per 10 μg/m 3 increase of pm2.5.
This study is in contrast to a report published in 2012, which is an increase in diabetes by 25 % in interquare nitrogen dioxide (no 2 ) in a cohort of black women who live in Los Angeles. Find diabetes and PM2.5 or PM10, but found an association with the "distance to the street", a replacement marker for traffic -related pollution. A borderline statistical context between confirmed cases of diabetes and no 2 levels. 5 pearson et al. reported in 2010 of a 1%increase in diabetes with an increase of 10 μg/m 3 of PM2.5.
This current Italian study indicates a greater risk of risk than Pearson, an increase of 35 % in men and an increase of 40 % in women per 10 μg/m 3 pm2.5. We should note that Pearson's cohort was exposed to lower PM2.5 concentrations-2.5 μg/m 3 to 17.7 μg/m 3 (median = 11 μg/m 3 )-compared to the people in this Italian study, their exposure 11 μg/m was 3 to 32 μg/m 3 with a higher median = 8.68 μg/m 3
There are mechanisms that explain a possible connection, in particular that the air pollutants increase the systemic oxidative stress and trigger inflammatory changes that lead to insulin resistance. brought. 9 In addition, an overview of how toxins can cause insulin resistance through a weakened thyroid function and mitochondrial damage.
Several studies now indicate that air filter systems indicate indoors by reducing the PM2.5 values, also reducing the markers for the risk of cardiovascular diseases. 11.12 With the same intervention method, the cleaning of the room air can possibly prove to be useful to treat insulin resistance, diabetes reduce and reduce the risk of diabetic complications and hospital admissions.

  1. Krämer U, Herder C, Sugiri D, et al. Traffic air pollution and type 2 diabetes: Results of the Salia cohort study. Environmental health perspective. 2010; 118 (9): 1273-1279.
  2. Chen h, burnett rt, kwong jc, et al. Risk for newly occurring diabetes in relation to long -term fine dust pollution in Ontario, Canada. Environmental health perspective. 2013; 121 (7): 804-810.
  3. Coogan Pf, White LF, Jerrett M, et al. Air pollution and incidence of high blood pressure and diabetes mellitus in black women who live in Los Angeles. traffic. 2012; 125 (6): 767-772.
  4. Puett RC, hard Je, Schwartz J, HU FB, Liese Ad, Laden F. Are fine dust loads connected to the risk of type 2 diabetes? Environmental health perspective. 2011; 119 (3): 384-389.
  5. Andersen ZJ, Raaschou-Nielsen O, Ketzel M, et al. Diabetes incidence and long-term pollution from air pollution: a cohort study. diabetes treatment. 2012; 35 (1): 92-98.
  6. Pearson JF, Bachireddy C, Shyamprasad S, Goldfine, Brownstein JS. Association between fine dust and diabetes prevalence in the USA diabetes treatment. 2010; 33 (10): 2196-2201.
  7. XU X, Liu C, XU Z, et al. Long -term exposure to fine dust pollution in the area leads to insulin resistance and mitochondrial changes in the adipose tissue. toxicol sci. 2011; 124 (1): 88-98.
  8. Sun Q, Yue P, Deiuliis yes, et al. The pollution of the ambient air exaggerates fat infections and insulin resistance in a mouse model for nutritional obesity. traffic. 2009; 119 (4): 538-546.
  9. Rajagopalan S, Bach approx. Air pollution and type 2 diabetes: mechanistic knowledge. diabetes. 2012; 61 (12): 3037-3045.
  10. Hyman M. System biology, toxins, obesity and functional medicine. aging Ther Health med. 2007; 13 (2): S134-S139.
  11. chen R., Zhao A., Chen H. et al. Cardiopulmonary advantages of reducing particles from free interior: a randomized, double-blind crossover study with air purifiers. j am Coll Cardiol. 2015; 65 (21): 2279-2287.
  12. Weichenthal S, Mallach G, Kulka r, et al. A randomized, double-blind crossover study on room air filtration and acute changes in cardiorespiratory health in a first nation. indoor air. 2013; 23 (3): 175-184.