Study: A high absorption of fiber by growing girls lowers the risk of breast cancer in adulthood

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Reference Farvid MS, Eliassassen Ah, Cho e, Liao X, Chen Wy, Willett toilet. Filling up in young adults and risk of breast cancer. Pediatrics. 2016; 137 (3): 1-11. Design This was a retrospective study that used data from the Nurse 'Health Study to determine multivariously adapted COX-proportional hazards models for relative risks (RRS) for breast cancer, based on how much fiber during the adolescence was consumed. Participants The Nurses' Health Study II (NHSII) is an ongoing prospective cohort of 116,430 registered nurses aged 25 to 42 when they were enrolled in 1991 20 years of follow -up. In 1998, 44,263 of these women also filled a questionnaire about their diet during ...
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Reference

Farvid MS, Eliassassen Ah, Cho e, Liao X, Chen Wy, Willett toilet. Filling up in young adults and risk of breast cancer. Pädiatrie . 2016; 137 (3): 1-11.

Design

This was a retrospective study that used data from the Nurse 'Health Study to determine multivariously adapted COX-proportional-hazards models for relative risks (RRS) for breast cancer, based on how much fiber was consumed during adolescence.

participant

The Nurses' Health Study II (NHSII) is an ongoing prospective cohort of 116,430 registered nurses aged 25 to 42 when they were enrolled in 1991 20 years of follow -up. In 1998, 44,263 of these women also filled out a questionnaire about their diet during the high school. In this sub -group, 1,118 cases of breast cancer were documented.

variable pursued

Total absorption of fiber, insoluble fiber and soluble fiber during adolescence and in early adulthood

target parameter

diagnosis with breast cancer

important knowledge

In all women, the overall absorption of fiber in early adulthood was connected by 19 % with a significant reduction in breast cancer risk (BC). The RR for the highest vs. lowest quintil was 0.81 (95% confidence interval [CI]: 0.72–0.91; p for trend = 0.002). A higher absorption of soluble fiber was associated with a 14 % lower risk (RR: 0.86; 95 % KI: 0.77–0.97; p = 0.02) and insoluble fiber with a 20 % reduced risk (RR: 0.80; 95 % CI: 0.71-0,90; p <0.001). The entire food fiber during the adolescence was also associated with a lower BC risk (RR: 0.84; 95 % CI: 0.70-1.01; p = 0.04). For 41,092 women, data on the absorption of fiber in both young people and in adults were available. When their average fiber intake was calculated for both periods, the RR was 0.75 (95 % KI: 0.62-0.91; p for trend = 0.004) when comparing the highest quintile.

practice implications

In recent years it has been shown that progression to breast cancer begins early in life. Exposure during childhood and youth influence the long -term risk of breast cancer. We have seen a flood of studies that examine the nutrition in pre-adolescence and adolescence and indicate that prevention efforts could be more effective if they are started in adolescence instead of adulthood. 1 Previous studies indicated that calorie restriction, poor food quality, a high overall fat and high alcohol absorption Could increase risk, but these studies were methodologically limited and the results were contradictory. Hopefully the recent studies have overcome these weaknesses and offer useful orientation aids.
breast cancer prevention must begin sooner than later in life.
The risk of abnormal cell changes is highest when the breast tissue grows the fastest - between the beginning of the menstruation of a young woman and her first fully held pregnancy. Interventions to prevent breast cancer are most effective when they are started at an early age and continued in the course of a woman's life.
This current paper, which was written by Maryam Farvid PhD and colleagues at the TH Chan School of Public Health in Harvard, is the latest in a recently published series about the diet of young people and the risk of breast cancer in adults.
Liu et al. in 2014 reported that fiber, vegetable proteins and nuts offer a protective advantage against breast cancer. A nutritional questionnaire was used in this Canadian cohort to compare nutrition between the ages of 10 and 15 and the risk of breast cancer diagnosis as an adult. Around 2,865 breast cancer cases were compared with 3,299 control cases and estimated ODDS ratios (ORS) and 95 % confidence intervals (CIS) were determined by logistical regression. Reversed associations between the absorption of fiber, vegetable protein, vegetable fat and nuts during adolescence with the risk of breast cancer were found, an association that remained after the admission of adults. In other words, consumption of fiber, vegetable protein, vegetable fat and nuts during adolescence was associated with a reduced risk of breast cancer. The ORS (95 %ki) for the highest vs. lowest quintile of intake was 0.66 (0.55–0.78; p for trend <0.0001) for fiber 0.80 (0.68-0.95; p for trend = 0.74 (0.63-0.87; p for trend = 0.002) for plant fat and 0.76 (0.61-0.95 for ≥1 portion/day vs. <1 portion/month income); p for trend = 0.04) for nuts. To put it easier: the consumption of many fiber, vegetable protein, vegetable fat and nuts reduced the risk of breast cancer by 34 %, 20 %, 26 %or 24 %.
This reduction in the risk of breast cancer, which is reported in this article by Liu, agrees with what Maryam Farvid reports in the current article.
one also by Farvid et al. The study of July 2015 was not a significant connection between a carbohydrate rich or a high glycemic diet during adolescence and breast cancer risk. Surprisingly, the study found that diets with high GI, GL, Insulin Index and Insulin pollution during adolescence or early adulthood were not associated with increased risk of breast cancer.
These results are also surprising because they are published by Minicozzi et al. From 2013, it seems to be determined in which a high factor and obesity increased the risk of death from breast cancer in hormone receptor -positive diseases significantly and independently.
The same team of researchers, Farvid et al., reported in April 2015 that meat consumption during adolescence was significantly associated with a higher precedentopausal breast cancer risk. When comparing the highest quintile of consumption, frequent meat eaters had a 43 % increased relative risk (RR: 1.43; 95 % KI: 1.05–1.94; p for trend = 0.007). This association did not apply to postmenopausal breast cancer. Overall, poultry was associated with a lower risk of breast cancer. The RR 0.76 (95 % AI: 0.60–0.97) for each portion per day. The replacement of a portion of red meat per day by a portion of a combination of poultry, fish, beans or nuts was associated with a 15 % lower risk of breast cancer (RR: 0.85; 95 % AI: 0.74–0.96). A 23 % lower risk of premenopausal breast cancer (RR: 0.77; 95 % KI: 0.64–0.92).
As the result of these recent studies, we collect knowledge that enable us to describe more precisely how a young woman should eat to lower her risk of developing breast cancer later in life. Your goal should be a diet that emphasizes fiber, vegetable proteins, vegetable fats, nuts and poultry and reduces meat consumption by replacing fish, poultry or beans. The reduction in the glycemic load can be useful or not.

  1. Mahabir S. Association between nutrition during the preadolescence and adolescence and breast cancer risk in adulthood. j adolesc health . 2013; 52 (supplement 5): S30-S35.
  2. Colditz GA, Bohlke K, Berkey CS. The risk of breast cancer begins early: prevention must also be. breast cancer treatment . 2014; 145 (3): 567-579.
  3. Liu Y, Colditz GA, Cotterchio M, Boucher BA, Kreiger N. fiber, vegetable fat, herbal protein and nut recording in adolescents and breast cancer risk. breast cancer treatment . 2014; 145 (2): 461-470.
  4. Farvid MS, Eliassassen Ah, Cho e, Chen Wy, Willett toilet. Carbohydrate amount and quality in young people and early adulthood in terms of breast cancer risk. biomarker for crab epidemics PREV . 2015; 24 (7): 1111-1120.
  5. Minicozzi P, Berrino f, Sebastiani f, et al. High sober blood sugar and obesity increase significantly and independently the breast cancer risk in hormone receptor -positive diseases. EUR J Cancer . 2013; 49 (18): 3881-3888.
  6. Farvid MS, Cho e, Chen Wy, Eliassassen Ah, Willett toilet. Meat consumption in adolescents and breast cancer risk. intj cancer . 2015; 136 (8): 1909-1920.