Study: Ashwagandha against male infertility

Die Studie untersucht die Wirkung eines Wurzelextrakts von Ashwagandha (Withania somnifera) auf die spermatogene Aktivität bei Männern mit oligospermischer Unfruchtbarkeit. Es handelt sich um eine doppelblinde, randomisierte, placebokontrollierte Pilotstudie mit 46 Teilnehmern. Die Behandlungsgruppe erhielt 12 Wochen lang dreimal täglich 225 mg Ashwagandha-Wurzelextrakt, während die Kontrollgruppe ein Placebo einnahm. Die Studie zeigt, dass die Spermienkonzentration bei den mit Ashwagandha behandelten Männern um 167 % anstieg. Dies legt nahe, dass Ashwagandha bei der Verbesserung der Spermienqualität bei Männern mit Unfruchtbarkeit hilfreich sein könnte. Referenz Ambiye VR, Langade D, Dongre S, Aptikar P, Kulkarni M, Dongre A. Klinische Bewertung der spermatogenen Aktivität …
The study examines the effect of a root extract by Ashwagandha (Withhania Somnifera) on spermatogenic activity in men with oligospermic infertility. It is a double -blind, randomized, placebo -controlled pilot study with 46 participants. The treatment group received 225 mg Ashwagandha root extract for 12 weeks a day, while the control group had a placebo. The study shows that the sperm concentration increased by 167 % of the men treated with Ashwagandha. This suggests that Ashwagandha could be helpful in improving sperm quality in men with infertility. Reference ambiye VR, Langade D, Dongre S, Aptikar P, Kulkarni M, Dongre A. Clinical evaluation of spermatogenic activity ...
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The study examines the effect of an Ashwagandha root extract on the spermatogenic activity in men with oligospermic infertility. It is a double -blind, randomized, placebo -controlled pilot study with 46 participants. The treatment group received 225 mg Ashwagandha root extract for 12 weeks a day, while the control group had a placebo. The study shows that the sperm concentration increased by 167 % of the men treated with Ashwagandha. This suggests that Ashwagandha could be helpful in improving sperm quality in men with infertility.

Reference

Ambiye VR, Langade D, Dongre S, Aptikar P, Kulkarni M, Dongre A. Clinical evaluation of the spermatogenic activity of the root extract by Ashwagandha ( withhania somnifera ) in oligospermic men: a pilot study. Evid Based Complement Alternate Med . 2013; 2013: 571420.

Design

double-blind, randomized, placebo-controlled parallel group pilot study

participant

68 Healthy men at the age of 22 - were evaluated with male infertility. Of these participants, 46 were recorded after they were considered suitable for the recording. The male factor was defined by a sperm concentration between 5 and 20 million/ml and a total motility of 10 %. - here and here .

If doctors determine that misalignment of the HPG contributes to male infertility, the Ashwagandha root can be recommended to improve seed parameters. Ashwagandha, a medicinal plant, the name of which on Sanskrit means "horse smell", 13 has been used for thousands of years to treat hypogonadism, low libido and male infertility. restored. The results of this study agree with an earlier study that showed that Ashwagandha improves the sperm parameters in sterile men with hypogonadism. 16 While this study lacked long-term follow-up and evaluation of the pregnancy rates under Ashwagandha treatment, the statistically significant improvement in the seed parameter, the lack of Side effects and side effects as well as the relative difficulty compared to techniques of assisted reproduction are considered the Ashwagandha root as part of a naturopathic approach to the treatment of male infertility, especially if a low testosterone level or a HPG dysregulation are jointly responsible.

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  8. Dandona P, Rosenberg Mt. A practical guide to male hypogonadism in primary care. int j clin practice . 2010; 64 (6): 682-696.
  9. Meeker JD, Godfrey-Bailey L, Hauser R. Relationships between serum hormone mirrors and seed quality in men from an infertility clinic. j Androl . 2007; 28 (3): 397-406.
  10. Coviello ad, Bremner WJ, Matsumoto Am, et al. With the serum mirrors comparable intratesticular testosterone concentrations, men who receive a hormonal contraceptive cure are not sufficient to maintain normal sperm production. j Androl . 2004; 25 (6): 931-938.
  11. Amory JK, Wang C, Swerdloff RS, et al. The effect of 5Alpha reductase inhibition with duta tastle and finasteride on seed parameters and serum hormones in healthy men. j clin endocrinol metab . 2007; 92 (5): 1659-1665.
  12. Büchter D, Behre Hm, Kliesch S, Nieschlag E. Pulsatile Gnrh or Humanes Choriongonadotropine/Humanes MenopausausaSengonadotropine as an effective treatment for men with hypogonadotropem hypogonadism: a review of 42 cases. EUR J ENDOCRINOL . 1998; 139 (3): 298-303.
  13. stearn wt. botanical Latin, history, grammar, syntax, terminology and vocabulary. wood press (OR); 1992.
  14. Meeker JD, Godfrey-Bailey L, Hauser R. Relationships between serum hormone mirrors and seed quality in men from an infertility clinic. j Androl . 2007; 28 (3): 397-406.
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  16. ibid.
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Die Studie untersucht die Wirkung eines Wurzelextrakts von Ashwagandha (Withania somnifera) auf die spermatogene Aktivität bei Männern mit oligospermischer Unfruchtbarkeit. Es handelt sich um eine doppelblinde, randomisierte, placebokontrollierte Pilotstudie mit 46 Teilnehmern. Die Behandlungsgruppe erhielt 12 Wochen lang dreimal täglich 225 mg Ashwagandha-Wurzelextrakt, während die Kontrollgruppe ein Placebo einnahm. Die Studie zeigt, dass die Spermienkonzentration bei den mit Ashwagandha behandelten Männern um 167 % anstieg. Dies legt nahe, dass Ashwagandha bei der Verbesserung der Spermienqualität bei Männern mit Unfruchtbarkeit hilfreich sein könnte. Referenz Ambiye VR, Langade D, Dongre S, Aptikar P, Kulkarni M, Dongre A. Klinische Bewertung der spermatogenen Aktivität …
The study examines the effect of a root extract by Ashwagandha (Withhania Somnifera) on spermatogenic activity in men with oligospermic infertility. It is a double -blind, randomized, placebo -controlled pilot study with 46 participants. The treatment group received 225 mg Ashwagandha root extract for 12 weeks a day, while the control group had a placebo. The study shows that the sperm concentration increased by 167 % of the men treated with Ashwagandha. This suggests that Ashwagandha could be helpful in improving sperm quality in men with infertility. Reference ambiye VR, Langade D, Dongre S, Aptikar P, Kulkarni M, Dongre A. Clinical evaluation of spermatogenic activity ...

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