Mega study with over 400,000 participants - intestinal bacteria related to cardiovascular & other health states
Mega study with over 400,000 participants - intestinal bacteria related to cardiovascular & other health states
intestinal bacteria related to dozens of health conditions
researchers have associated intestinal bacteria and other microorganisms with dozens of health states. According to studies presented at the Virtual Annual Congress of the European Society for Cardiology, there is a connection between intestinal bacteria and high blood pressure, type 2 diabetes and chronic obstructive lung diseases.
Hilde E. Groot, MD from the University of Groningen in the Netherlands, spoke in her lecture on how much information intestinal bacteria can provide. "Our study shows that microbiota could play an important role in maintaining health and could help us develop new treatments," said Dr. Groot. She added that “the extent to which the human intestinal microbioma can be regarded as a determinant for illness and healthy aging is unknown.
The human intestinal microbiomous consists of the microorganisms in the digestive tract. These are generally bacteria and individual organisms that are called archae. These microorganisms also have genetic material. In the past, small studies have shown that there is a connection between intestinal bacteria and certain diseases.
The team of Dr. Groot did a large -scale study to determine whether this is the case. They examined 422,417 adults that were not related to British Bio Chances. They had undergone genotyping to identify their genetic material and provided information on various diseases and health states, including blood pressure and BMI. The average age of the participants was 57 years and 57% of them were women.
specific diseases and intestinal bacteria
The researchers learned that there was a connection between higher concentrations of 11 types of intestinal bacteria with 28 health and illness results. These results included type 2 diabetes, heart failure, hypercholesterolemia, osteoarthritis and kidney failure.
The bacteria associated with high blood pressure are referred to as ruminococcus flavefaciens. Clostridium is associated with the number of platelets.
The researchers also found relationships between certain types of intestinal bacteria and high blood pressure, BMI, high blood fats and the frequency of alcohol consumption. There was also a connection with atopia, a genetic tendency to develop allergic problems such as asthma and eczema.
In her lecture, Dr. Groot the connection between intestinal bacteria and alcohol consumption. She said: "What we eat and drink is related to the microbiome content. That is why we have examined the connections with meat, caffeine and alcohol. We more often observe a connection between increased methanobacterium levels and alcohol consumption. It is important to emphasize that this is a connection, no causal connection, and that further research is required."
major study of intestinal bacteria
The size of this study makes it exceptional. With more than 400,000 participants, the researchers were able to draw clearer conclusions.
"In recent years, research on the human intestinal microbioma and the connections with health and illness has increased enormously. However, most studies have examined one or more features. The strength of our study is the possibility of covering a variety of characteristics within a population," said Dr. Groot.
dr. Groot regards this study as a supplement to previous studies that indicate that there is a connection between the intestinal microbioma and the health results. She believes that further research is necessary before members of the health professions can use the intestinal microbioma to advise their patients.
"Follow-up studies are necessary to examine the causality before the public and the members of the health professions are specifically advised. This study provides information on where to go," she concluded.