Xylooligosaccharide: The low -dose prebiotic
Xylooligosaccharide: The low -dose prebiotic
xylooligosaccharides: the low -dosed prebiotic
by Prof. Gene Bruno, MS, MHS, RH (AHG)
Huntington University of Health Sciences
food pretreatment are typically indigestible fiber connections that undigest the upper part of the gastrointestinal tract (GI) and the growth or activity of friendly, probiotic bacteria that colonize the colon by acting as a substrate for you are several pre-biotics to choose from Are fructooligosaccharides. Whatever the type, a common feature is that typically several grams are required to achieve clinical benefits. However, there is an exception: xylooligosaccharides (XOS) that have been proven to offer prebiotic advantages with only one dose of 1.032 to 1.4 g.
What is XOS?
XOS mainly consist of two or three xylose units with beta-1.4 linkages. They are obtained by hemicellulose hydrolysis, which occurs relatively frequently in the cell walls of grain. XOS increases the number of intestine bifidobacterium in humans and holds the water content in the stool in the normal range.2
What is the proof?
in a double -blind, randomized, placebo -controlled study received 3 healthy adults (n = 32) 1.4 g XOS, 2.8 g XOS or placebo in daily cans. The study consisted of a two-week run-in, an eight-week intervention and a two-week Washout phase. Stool samples were removed at the beginning of the study, after four and eight weeks of intervention and two weeks after the intervention was completed. The rehearsals were subjected to a culture, pyrosquencing of community DNA, pH and SCFA analyzes. The tolerance was assessed by daily symptom diagrams. The results were that XOS was tolerated without significant gastrointestinal side effects and bifidobacteria The number rose in both XOS groups compared to the placebo test subjects. The group with 1.4 g per day had a significant higher bifdobacteria counts compared to the subjects of the placebo group after eight and 10 weeks. The researchers came to the conclusion that an XOS supplementation "can be advantageous for the gastrointestinal microbiota" and "the low-required dose and the lack of GI side effects make it possible to use XOS as a dietary supplement".
conclusion
It should be pointed out that the minimum effective dose of 1.4 g was based on a 70 percent XOS material in the XOS study mentioned above. Therefore, 0.98 g XOS was the yield (ie 1.4 x 70 percent = 0.98). However, a 95 percent XOS material is also available, so that only 1.032 g would be necessary to result in the same 0.98 g. In any case, XOS seems to offer the lowest effective dose of all prebiotics currently used.
references:
Professor Gene Bruno, MS, MHS, The provost for Huntington College for Health Sciences, is a nutritionist, herbalist, author and educator. For more than 37 years, he has trained and trained natural product retailers and medical staff, researched and formulated natural products for dozens of food supplements and formulated articles on nutrition, herbal medicine, nutrials and integrative health issues for trade and consumers. It can be reached at gbruno@hchs.edu.
- 4 frames
- beta-1
- bifidobacterium
- clinical benefit
- double -blind
- fructooligosaccharides
- gastrointestinal tract
- gastrointestinal tract
- indigestible fiber
- placebo-controlled study
- prebiotic advantages
- prebiotics
- Prof. Gene Bruno Blog
- pyrosquencing
- random
- undigid
- XOS
- xylooligosaccharides
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