Sucralose damages the DNA, combined with leaky: study

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In the course of history, people are committed to the sweet taste of sugar, the perfect addition to our natural palate. However, concerns about the health effects of sugar have led to the development and widespread use of sugar substitutes such as sucralose and aspartame. They first appeared in the middle of the 20th century, especially Saccharin. Aspartam was approved by the FDA in 1981 and Sucralose (brand name Splenda) came onto the market in 1998. Today these sugar substitutes are omnipresent in our diet and contained in a variety of processed foods and drinks. However, the use of such sugar substitutes is increasingly controversial, since new scientific studies ...
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In the course of history, people are committed to the sweet taste of sugar, the perfect addition to our natural palate. However, concerns about the health effects of sugar have led to the development and widespread use of sugar substitutes such as sucralose and aspartame. They first appeared in the middle of the 20th century, especially Saccharin. Aspartam was approved by the FDA in 1981 and Sucralose (brand name Splenda) came onto the market in 1998. Today these sugar substitutes are omnipresent in our diet and contained in a variety of processed foods and drinks.

However, the use of such sugar substitutes is increasingly discussed controversially, since new scientific studies indicate considerable health risks, including potential genotoxic effects and harmful effects on intestinal health. A recently in the Journal of Toxicology and Environmental Health, part B, provided particularly alarming knowledge of sugar substitutes sucralose [1].

sucralose and DNA damage

  1. The experiment:

    In the study, the researchers exposed human blood cells and intestinal tissue to a sucralose derivative called Sucralose-6-acetate.

  2. The results:

    The results indicate that sucralose can cause DNA fragmentation, which may increase the risk of illness. These results support earlier research results that associated sucralose with intestinal health problems [2].

    3. The consumption of sucralose means that the body produces sucralose-6 acetate, a substance that is now considered genotoxic, i.e. is able to damage the DNA. It is worrying that sucralose-6 acetate was also found in traces in commercially available products, in concentrations that overturned the safety limit values ​​defined in Europe.

    sucralose. E955. Artificial sweetener and sugar substitute. Structural chemical formula and molecule 3D model. C12H19CL3O8. Atoms with color coding. Vector illustration

    The consequences of such DNA damage can range from accelerated aging to an increased risk of cancer. Susan Schiffman, PhD, one of the researchers involved in the study, emphasized to review the security and regulatory status of sucralose and asked people to avoid products that contain sucralose [1].

    sucralose and Leaky Gut syndrome

    The same study also linked Sucralose to the Leaky Gut syndrome, a state in which the intestinal mucosa is worn out and permeable. This can lead to symptoms such as digestive pain, flatulence, flatulence and diarrhea [2].

    sugar substitutes, weight gain and blood sugar levels

    Contrary to the original goal that these substances should support weight control, various studies indicate that paradoxically, they can contribute to weight gain and to impair blood sugar control [3].

    1. increased appetite:

      Although artificial sweeteners are calorie -free, they can increase the appetite and thus calorie intake and lead to weight gain.

    2. changed intestinal microbiom:

      These sweeteners can also change our intestinal microbiota, influence the metabolism and possibly increase weight gain and an impaired glucose control.

    3. insulin resistance:

      The regular consumption of artificial sweeteners can cause insulin resistance, a preliminary stage of type 2 diabetes.

      4. natural alternatives to sugar

      While sugar substitutes can hide risks, there are natural alternatives that can breastfeed our appetite for sweets without having a negative effect on health:

      1. stevia:

        stevia is obtained from the leaves of the stevia rebaudiana plant and is a calorie -free sweetener that has been proven to have potential health benefits, such as reducing blood pressure and blood sugar level [4].

      2. MönchsfruchtSweetfstoff:

        This sweetener obtained from monk fruits is calorie -free and potentially advantageous for weight control and the treatment of diabetes [5].

      3. raw honey:

        In addition to its sweetening properties, raw honey is rich in antioxidants and has anti -inflammatory properties [6].

        4. attitude of the FDA to sucralose

        Despite the alarming results of these studies, the FDA remains with its attitude to the safety of sucralose and emphasizes that sucralose is 600 times sweeter than household sugar and widespread baked goods, chewing gum, gelatin and frozen milk desserts [7]. The attitude of the FDA is based on more than 110 studies that were carried out to identify potential toxic effects, including effects on the reproduction and nervous system, carcinogenicity and metabolism. In addition, clinical studies have been checked in humans to determine the metabolism and the effects on patients with diabetes.

        possible health risks of other sugar substitutes

        Also aspartam, another popular artificial sweetener, is not free of controversy. Some studies associate aspartame with headaches, dizziness and mood swings [8]. Despite the assurance of security by the FDA, many health -conscious people and experts are careful due to these possible side effects.

        The role of nutrition and lifestyle for health

        While sugar and its alternatives play an important role in our health, it should not be forgotten that general nutrition and lifestyle also play a crucial role. Regular physical activity, a balanced diet with lots of fruit and vegetables, sufficient sleep and stress management are important components of a healthy lifestyle.

        conclusion: The future of sugar substitutes

        In summary, it can be said that increasing consumption and the resulting concerns of sugar substitutes underline the need for more extensive and stricter studies. While these substitutes represent an apparently attractive solution for excessive sugar consumption, the potential health risks can destroy their advantages. It is therefore important to tackle the consumption of these substances with caution and an informed perspective. Consumers can also consider trying out natural alternatives or reducing their overall absence of sweetened products to improve their health results.

        The debate about sugar substitutes is part of a larger story about processed foods and additives, a topic that continues to attract attention because we are trying to make healthier decisions in our eating habits.

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