Rare diagnosis: breast implant-accompanying lymphoma or pericardium?

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A 58-year-old woman shows a rare case of breast implant-associated alcl with malignant pericarder cast. Early detection is crucial. Symptoms: breast pain, fever, hemodynamics unstable.
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This research report describes a rare case of breast-grid-associated anaplastic large-cell lymphoma (Bia-Alcl), in which the disease initially showed itself through a malignant fluid accumulation in the pericardium (MPE). The patient, a 58-year-old woman, came to the hospital with symptoms such as stinging chest pain, fever and chills after removing her breast implants.

The clinical examination showed signs of a pericarda ponade, a life -threatening situation in which the pericardium is expanded by excess liquid, which hinders the normal heartbeat. A echocardiography confirmed a large fluid accumulation in the pericardium. After a cross -subject discussion, a pericardiocentesis was carried out, a procedure in which the excess liquid is removed. This brought immediate relief of the symptoms.

The analysis of the displaced liquid confirmed the diagnosis: Bia-Alcl, a rare lymphoma type that is related to breast implants. The treatment immediately started with a combination of the medication Brentuximab, Cyclophosphamide, Doxorubicin and Prednisolon. This emphasizes the importance of also considering rare diseases when it comes to collecting fluid accumulation in the pericardium in patients with breast implants.

Potential future consequences or changes in previous practices

The knowledge from this case could lead to increased awareness of Bia-Alcl in medical practice, especially in patients who have or have breast implants. It could attract greater attention to the symptoms of a pericarda ponade in these patients. In the future, doctors in women with breast implants and unclear heart problems could often consider that a lymphoma could be the cause. This could lead to a faster diagnosis and more effective treatment.

Basic terms and concepts

  • breast implant-associated anaplastic large cell lymphoma (Bia-Alcl): A rare form of lymphatic cancer connected to breast implants.
  • malignant fluid accumulation in the pericardium (MPE): A dangerous accumulation of cancer cells and liquid in the pericardary that can affect the heartbeat.
  • pericardiocentesis: A medical procedure to remove excess liquid from the pericardium.
  • Hasolybumponade: A medical emergency situation in which liquid fills the space around the heart and thus impairs its normal function.

abbreviations

  • bia-alcl: breast implant-associated anaplastic large cell lymphoma
  • mpe: malignant pericardial casting (malignant fluid accumulation in the pericarda)
  • CD30+, Alk-: Specific markers that can be detected in lymphomas

maligner pericardian casting as a rare initial manifestation of Bia-Alcl

The present study reports on a rare occurrence of breast implant-associated anaplastic large-cell lymphoma (Bia-Alcl), in which malignant pericarder casting (MPE) served as a primary manifestation. The case concerns a 58-year-old woman who was presented with pleuric chest pain, fever and chills after removing her breast implants.

Clinical presentation and diagnosis

In the clinical examination, jugular vein congestion, subdued heartbeat and hemodynamic instability showed themselves in the clinical examination. An echocardiogram with Doppler confirmed a large pericardial cast with tamponade physiology. During a multidisciplinary discussion, the decision was made to carry out a diagnostic and therapeutic pericardiocentesis that caused immediate symptomatic relief.

The cytology studies of the pericardial fluid were carried out, with CD30+ and Alk-Alcl being found, which confirmed the diagnosis of Bia-Alcl.

therapy and meaning

Immediately after the diagnosis, therapy with Brentuximab in combination with cyclophosphamide, doxorubicin and prednisolone began. This case underlines the rarity of MPE as an initial presentation of Bia-Alcl and emphasizes the importance of early detection and consideration of rare lymphomas in patients with breast implants.

FAZIT

The study teaches the importance of mpe alcohol in the differential diagnostic consideration of MPE, especially in patients with breast implants.

In addition, the case illustrates the life -saving possibility of pericardiocentesis in tamponade and the need for an immediate oncological therapy after the diagnosis.

For further details and the full study please visit this link .