Magic Mushrooms: A single dose can alleviate treatment -resistant depression symptoms

Magic Mushrooms: A single dose can alleviate treatment -resistant depression symptoms

depression is a mental illness that affects millions of people worldwide. According to the World Health Organization (WHO), Major Depression (MDD) is the most common form of depression and is characterized by persistent feelings of sadness and/or loss of interest in activities that used to be fun. Treatment -resistant depression (TRD) is a type of MDD that does not respond to conventional treatments such as antidepressants or psychotherapy. It is estimated that up to 30 % of people with MDD are affected by TRD.

"Over the years, researchers have examined the use of psychedelic substances that change the mood, thoughts or sense of a person - as a therapy option for treatment -resistant depression.

One of these psychedelic drugs is psilocybin. Earlier research show that psilocybin has antidepressant effects in people with TRD and reduces depressive symptoms in patients with treatment -resistant depression.

What is psilocybin?

psilocybin is a naturally occurring psychedelic connection that occurs in certain mushrooms. Psilocybin has been used for ceremonial and healing purposes in various cultures around the world for centuries. It has a chemical structure similar to serotonin, a neurotransmitter that helps to regulate the mood and work by binding to serotonin receptors in the brain.

The studies

A new clinical study with 22 locations has found that a single dose of psilocybin, a psychedelic chemical that occurs in certain mushrooms, could help reduce depression symptoms in people with TRD.

The study published in * the Lancet Psychiatry * provides evidence that PSILocybin could be a practical treatment option for people who have to deal with mental disorders. The participants received either a single dose of psilocybin or an inactive placebo. The participants who received psilocybin reported a significant decrease in depression symptoms in the follow -up examinations after 1 week and 3 months compared to those who received the placebo.

The researchers also found that the effect of psilocybin was long -lasting. During the follow -up examination after 3 months, 57 % of the participants who received the psilocybin were in the remission of their depression compared to only 28 % of the participants who received the placebo.

side effects

The researchers also reported some adverse side effects of this treatment, including suicide thoughts. However, the researchers found that these thoughts were not reacted to and the depression symptoms of the participants were reduced.

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