Dental Revolution: The drug therapy for dental regeneration is to be carried out in clinical studies in humans next year

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tooth loss is a big problem for many, especially for older people. According to the CDC, 17 percent of the elderly in the United States have lost all teeth. This can dramatically affect your quality of life, restrict your nutritional opportunities and impair your self -esteem.

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However, Japanese researchers at the Graduate School of Medicine at the University of Kyoto have recently worked on a groundbreaking solution: drug therapy that is supposed to stimulate tooth regeneration. Reports of Japanese media indicate that the first clinical studies in humans for this promising drug could begin next year. If everything goes well, the treatment of tooth growth could be available to the general public by 2030.

The basis: USAG-1 protein and tooth growth

The basis for this potential breakthrough is a study from 2021, which was carried out by the same research team. The study showed the important role of a protein called USAG-1 in regulating tooth growth. This protein suppresses tooth development, and by deactivating the gene that triggers the USAG-1 production, the researchers found that mice could grow their teeth in a natural way.

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the journey ahead: to try animal models on humans

While the first research and animal experiments provide promising results, the next challenge is to implement these findings into practical, safe and effective treatment for humans. As the Mainichi newspaper reports, the researchers are planning to start clinical studies in July 2024.

Katsu Takahashi, head of the dentistry and oral surgery department at the Kitano Hospital of the Medical Research Institute in Osaka, expresses his enthusiasm and optimism with regard to the prospects of the study. "The idea of ​​growing new teeth is every dentist's dream. I have been dealing with it since I was my doctoral student. I was confident that I would make it," Takahashi told the newspaper.

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he added: "We hope to pave the way for the clinical use of the drug."

a possible solution for a global problem

tooth loss is a common problem in many countries, especially among the older generation. Statistics are worrying in the USA: more than 25 percent of adults aged 65 and over have eight or fewer teeth, and 17 percent have lost all teeth. This not only represents a health problem, but also represents a significant obstacle to maintaining a healthy diet and the general quality of life. @Media (Min-Width: 0PX) {#Div-Gpt-Ad-Healthy_holistic_Living_Com-Large-Leader Board-2-0-Asloaded {Max-Width: 336px! Important; Max-Height: 280px! Important;}}

The new treatment developed in Japan could revolutionize dental care and give people who suffer from tooth loss, the opportunity to grow up their lost teeth naturally. The process described by researchers, which initiates a "third generation" of the ray regeneration, imitates natural tooth development, which is observed in children when they lose their milk teeth and grow permanent adults.

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The way to revolutionary dental treatment

Even if the prospect that medication for dental regeneration will be available by 2030 may sound too optimistic, the Japanese research team is convinced that they are on the right track. They assume that the clinical studies will deliver positive results and ultimately lead to a great revolution in dental care.

Although the development is still in an early stage, the view of this new therapy in the scientific community and beyond has caused excitement. In the event of success, it could change the life of millions of people around the world that suffer from tooth loss.

The way to a new era of dental treatment is full of challenges, but the breakthroughs previously achieved by the University of Kyoto are a glimmer of hope. While we are looking forward to the fact that clinical studies on humans will begin next year, the possibility of a world in which tooth loss can effectively can be reversed seems to be no longer to be science fiction. This treatment has the potential to change dental care as we know it and to make tooth loss from a permanent state of temporary inconvenience. We look forward to further developments in this exciting research area.

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