Study: sesame oil and diabetes

Reference

Sankar D, Ali A, Sambandam G, Rao R. Sesame oil shows a synergistic effect with anti-diabetics in patients with type 2 diabetes mellitus. Clin nutr. 15. December 2010. (Epub before printing)

Design

This open study included 60 patients with type 2 diabetes mellitus, divided into three groups; 18 patients received sesame oil, 20 patients took a daily dose of glibenclamide (glyburide) and 22 patients took both sesame oil and gliblamide. The patients of the sesame group were supplied with sesame oil and instructed to use about 35 grams (about 2.4 tablespoons) per day for cooking for 60 days. At the beginning and after 60 days of the experiment, blood samples were taken for analysis.

most important knowledge

In this group of type 2 diabetics, sesame oil had a synergistic effect with glibenclamide. The combination therapy lowered blood sugar and hemoglobin A1C significantly more than oil alone or medicines.

The total cholesterol level of 20 %, the LDL cholesterol level fell by 33.8 %and triglyceride values ​​by the total cholesterol level by those who only received sesame oil. For those who received both sesame oil and gliben clamid, these numbers were even better: 22 %, 38 %and 15 %. The HDL value rose by 15.7 % for the sesame oil patients and in the patients who received the combination of oil and medicine, by 17 %.

The combination therapy lowered the blood sugar and the hemoglobin A1C significantly more than oil alone or medicines alone.

effects on practice

This is not the first study to indicate that a dietary supplement with sesame oil is an advantage for diabetics. In a work from 2005 about rats with chemically induced diabetes, Ramesh et al. Chemically induced diabetes that sesame lignanes not only improved the lipid profile, but also significantly reduced the peroxidation of the LDL cholesterol.

in 2006 Sankar et al. About the results of her pilot study on 40 hypertensive diabetics who found that eating sesame oil in hypertensive diabetics, which were treated with atenolol and glibenclamide, had significant effects. The patients switched to sesame oil for 45 days and then switched to other oils such as palm or peanut oil for another 45 days. During the sesame oil part of the study "Sunk Systolic and Diastolic Blood Printing clearly." When the oil substitution was lifted, the BP values ​​rose again. ” During the study of the study, the body weight, the body mass index, the waist size, the hip size and the ratio of waist to hip this also applies to plasmaglobin A1c, overall cholesterol and triglyceride. In view of these results, it now seems sensible to propose a small experiment to their type 2 diabetics. Just let them eat sesame oil for eight weeks and observe whether your lipid profile improves.

In view of the parameters that are improved by sesame oil, we have to ask ourselves whether it may benefit people with metabolic syndrome. It could be worth considering to propose a similar experiment to people with metabolic syndrome.

By the way, there has also been interest in the ability of sesame oil to accelerate wound healing.