Study: magnesium and high blood pressure
Study: magnesium and high blood pressure
The present study deals with the effect of a magnesium supplement on blood pressure. The authors carried out a meta -analysis in which they examined 22 studies with a total of 1173 participants. They found that a magnesium supplement leads to a significant reduction in blood pressure. In crossover studies in particular, a stronger blood pressure reduction could be observed. It was also shown that a higher magnesium dose led to a lower reduction in blood pressure. The authors emphasize that further studies are necessary in order to determine the effect size. However, the most important message of the study is that magnesium can actually lower blood pressure and thus represents a possible alternative to blood pressure -lowering medication.
Reference
Kass L, Weekes J, Carpenter L. Effect of a magnesium supplement on blood pressure: a meta -analysis. EUR J Clin nutr. February 8, 2012. DOI: 10.1038/EJCN.2012.4. [Epub Ahead of Print]
Design
meta -analysis. Of the 141 identified work, only 22 studies with 23 records (n = 1,173) and a follow -up time of 3 to 24 weeks met the inclusion criteria with a supplemented elementary magnesium range of 120–973 mg (medium dose 410 mg). ).
most important knowledge
In crossover studies, there was a stronger reduction in blood pressure. This means that if people with high blood pressure do not take magnesium, their blood pressure was higher; When they took magnesium, their blood pressure was lower. In addition, the higher the magnesium dose, the lower the blood pressure. The combination of all studies showed a decline in systolic blood pressure (SBP) by 3–4 mmHg and the diastolic blood pressure (DBP) by 2–3 mmHg, which increases in crossover studies and an intake of> 370 mg/day. The authors came to the conclusion that a magnesium supplement apparently causes a small but clinically significant reduction in blood pressure. They demanded more studies.
effects on practice
The most important message of this meta -analysis is that magnesium actually lowers blood pressure.
We have to consider that meta -analysis homogenized all available information in a large mixer and comes to a number that is not necessarily the final answer to the question of the study. In the words of the authors: "This meta -analysis was carried out in order to evaluate the effect of a magnesium supplement [Blood Pressure] and to determine the characteristics of the studies that have the greatest effect size."
The authors found that the higher the amount of magnesium, over 370 mg/day, the stronger. None of the 22 selected studies calculated the food intake of the test subjects. The subjects came from 12 different countries, so we cannot know whether one of them had a magnesium deficiency right from the start. There are many other variables in such an analysis, but despite all the disadvantages we should remember the conclusion and build on this result.
For example, a dose of 370 mg elementary magnesium is clinically hardly the recommended daily dose, a value that prevents clinical magnesium deficiency symptoms. Magnesium -given magnesium is usually done in a higher dosage.
On the basis of this study, you can tell your patients that in numerous clinical studies it has been proven that magnesium reduces blood pressure.
Im magnesium miracle I wrote: "25 years of research that is necessary under ideal conditions about 300 mg of magnesium is only to compensate for the daily losses. Since the body only absorbs half of the amount absorbed, researchers assume that most people would benefit from a magnesium supplement. To supply body areas with vital magnesium.
"If you are under easy to medium -heavy stress caused by a physical or mental illness, a physical injury, sporting exertion or an emotional upheaval, your need for magnesium from 6 mg/kg/day increases up to 10 mg/kg/day. Dental products,
On the basis of this study, you can tell your patients that in numerous clinical studies it has been proven that magnesium reduces blood pressure. And with other lifestyle events, nutritional changes and nutritional supplements, patients can often do without blood pressure -lowering medication that can cause a magnesium deficiency in turn.