Early for dinner and late in bed, the risk of cancer can lower

reference

Kogevinas M, Espinosa A, Castelló a, et al. Effecting false eating habits on the risk of breast and prostate cancer (MCC Spain study) [Published Online Ahead of Print July 17, 2018]. intj cancer . https://onlinelibrary.wiley.com/doi/epdf/10.1002/ijc.31649.

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population-based case control study

participant

The data comes from MCC-Spain, a population-based multicase control study (MCC), which was carried out in 12 regions of Spain from 2008 to 2013. The larger MCC study includes cases of 5 tumor species and population controls. This sub -analysis included data from men and women between the ages of 20 and 85 with histologically confirmed cases of breast cancer (1,738 women) and prostate cancer (1,112 men). After the exclusion of people who had ever worked, the final analysis included 621 cases of prostate cancer and 1,205 cases of breast cancer. The population controls included 872 men and 1,321 women who were frequently selected from primary health centers and, according to gender, geographical field and age,.

study parameters evaluated

The participants were interviewed at the time of meals, sleep and chronotype and filled out a questionnaire for frequency of food.

target parameter

Prostate or breast cancer

important knowledge

Compared to participants who went to sleep immediately or shortly after dinner, participants who delayed falling asleep at 2 or more hours after dinner had a 20 % lower risk of breast and prostate cancer (adapted opportunities for opportunities [OR]: 0.80; 95 % confidant interval [CI]: 0.67–0,96) and each cancer (prostate cancer OR: 0.74; A similar association was observed among participants who had eaten before 9:00 p.m. compared to those who eaten their dinner after 10:00 p.m.

The effect of a longer dinner-to-sleep interval was more pronounced among those who adhered to other recommendations for cancer prevention (OR [Both Cancers]: 0.65; 95 % KI: 0.44–0.97) and for Morgent types (or [Both Cancers]: 0.66; 95 % CI: 0.49-0.90). Those who earned both an earlier dinner (before 9:00 p.m.) as well as a longer interval between dinner and sleep (≥ 2 hours) had an approximately 25 % lower combined risk of cancer (OR: 0.76; 95 % AI: 0.57–1.0). who had eaten after 10 p.m. and had a short dinner sleeping interval (<2 hours).

In summary, compliance with daily eating behavior and in particular a long interval between the last meal and sleeping was associated with a lower risk of cancer.

practice implications

In 2007 the International Agency for Cancer Research (IARC) published an explanation that shift work that disturbs the circadian rhythm is probably carcinogenic for humans.

In addition, experimental and epidemiological data have associated a chronic circadian disorder with a number of other chronic diseases, including diabetes, obesity, cardiovascular diseases and others.

If we ask our patients about their sleeping habits and find that they go to bed too early after dinner, it can reduce their risk of cancer, to encourage them to change this habit.

Obviously there is something about sleep patterns that affect health. A study in June 2018 examined the effects of meals that are not synchronized with the inner circadian watch on the plasma protein mirror during a day. Of 1,129 proteins analyzed, about half (573) fluctuated in the crowd during a 24-hour circadian cycle. The authors came to the conclusion that the circadian misalignment changes the biological signal paths of 127 proteins, signaling pathways that are related to immune function, metabolism and cancer. ^{5 The currently tested study suggests that the time of meals could also have an effect in relation to falling asleep.}

Most studies on nutrition and cancer have focused on the type of food consumed, either macromolecules or certain foods containing certain phytonutrients, and not at the time of meals. Nevertheless, a small number of studies have examined eating habits. For example, a study by Marinac et al. from 2016 (checked in this journal) that longer fasting at night is associated with a lower risk of recurring breast cancer.

This current study adds our understanding of the connections between the time of meals, sleep and cancer several new ideas that could have clinical relevance.

Firstly, falling asleep was associated with an increased incidence of breast or prostate cancer immediately after dinner. A sleep delay of just 2 hours reduced the combined risk of these cancer types by 26 % for prostate cancer and 16 % for breast cancer. If we ask our patients about their sleeping habits and find that they go to bed too early after dinner, it can reduce their risk of cancer, to encourage them to change this habit. You could choose either to eat dinner earlier or go to bed later. Given the results of Marinac et al. a previous dinner could be more advantageous.

Secondly, the early dinner also lowered the risk of cancer. We have to consider that this data comes from Spain, where the cultural standard is to postpone dinner for American conditions relatively late into the night. In this study, the meal was associated with a risk of cancer less than 35 % before 9 p.m. than the food after 10 p.m. How this affects people in the United States that usually eat around 6 p.m. is unclear.

The best idea is to combine both practices by eating early and falling asleep by delaying a few hours after eating.

Thirdly, the influence of the time of meals varied through certain general features. The data has been analyzed according to the person's chronotype, a concept that has recently attracted attention. The authors of the study describe the chronotype as "a human feature with a genetic basis that correlates with the daily preference for activities in the morning or evening." To put it simply, the chronotype indicates whether a person can be better referred to as a "night school" or "early riser". The protective advantages of meal times and sleep patterns were larger for chronotypes that preferred morning activity; Morge types had a 34% reduction in cancer risk compared to only 14% reduction in night types. The time of meals and sleeping made a greater difference in early risers than with night owls.

This study supports a number of traditional naturopathic concepts, especially early food. It also indicates that simple interventions and changes in the lifestyle can have a significant impact on the risk of cancer.