Nutrition, nutritional supplements and Parkinson's disease

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Cover Mischley LK, Lau RC, Bennett approx. The role of nutrition and nutritional supplements when Parkinson's disease progresses. Oxid Med Cell Longev. 2017; 2017: 6405278. Design This study was a cross-sectional analysis of an online platform created by the author (Laurie Mischley, ND, PhD). The platform takes Parkinson's patients into a longitudinal research study. The patients themselves report on their Parkinson's symptoms, their diet diary and the use of nutritional supplements. Participants included 1,053 people with idiopathic Parkinson's disease; 93 % of the participants were Caucasians, with an average of 5.2 years since the diagnosis. Study parameters evaluated Parkinson's symptoms, severity of progress, nutrition (after recall) and taking nutritional supplements; The …
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reference

Mischley LK, Lau RC, Bennett approx. The role of nutrition and nutritional supplements when Parkinson's disease progresses. oxid med Cell Longev . 2017; 2017: 6405278.

draft

This study was a cross-sectional analysis of an online platform created by the author (Laurie Mischley, ND, PhD). The platform takes Parkinson's patients into a longitudinal research study. The patients report on their Parkinson's symptoms, their dietary diary and the use of nutritional supplements.

participant

The study population included 1,053 people with idiopathic Parkinson's disease; 93 % of the participants were Caucasians, with an average of 5.2 years since the diagnosis.

study parameters evaluated

Parkinson's symptoms, severity of progression, nutrition (after recall) and taking nutritional supplements; The symptoms were assessed on the basis of the results reported by patients in the Parkinson's disease scale (Pro-PD), a result tool created by the author.

Primary result measurements

The analysis compares the disease progression rate of each patient with his diet and taking nutritional supplements to look for statistically significant contexts.

important knowledge

The following results show which food and nutritional supplements significantly ( p <0.05), which are associated with a slow progression or a faster progression of Parkinson's symptoms.

Delayed progress faster progress
fresh fruit and vegetables fruit and vegetables in cans
nuts and seeds diet and non-diet soda
non -fried fish fried foods
olive oil beef
wine ice cream
coconut oil yogurt
fresh herbs and spices cheese
Coenzyme Q10 iron
fish oil

practice implications

Parkinson's disease is an extremely weak disease and is hardly understood. 1 conventional options are limited, and studies indicate that many Parkinson's patients of a diet, naturopathy and nutritional supplements are turning to slow down the disease. However, little is known about its effectiveness. The present study is an attempt to shed light on the effects of nutrition and taking nutritional supplements to the progress of Parkinson's disease.

Many of the results of this study are not too surprising. Most foods associated with a delayed progression are elements of a Mediterranean diet. This type of nutrition has an anti-inflammatory effect and is demonstrably associated with fewer cases and a later outbreak of Parkinson's disease. 3 Fischöl has repeatedly proven to be a neuroprotective 4 and in fact this study found a connection between fish consumption and a delayed progression of the Parkinson's symptoms.

Most foods associated with a delayed progression are elements of a Mediterranean diet.

The connection between consumption of canned goods and a faster progression of Parkinson's disease is fascinating. Since this connection also remained after adjustment of income, it is less likely that it will be associated with limited access to health care (which is often associated with low income status). Could there be something in the cans themselves? The authors postulate that bisphenol A (BPA) or aluminum, a well -known neurotoxin, 5 could be subject to contributions

The association of lemonade consumption with a faster progression of the disease can be due to certain neurotoxins such as aspartame. 6 The association with fried foods can be related to lipid peroxidation. The association of ice cream, yogurt and cheese with quick progress is in line with previous research results; A meta-analysis of the absorption of dairy products and Parkinson's disease showed a dose-dependent connection between the absorption of dairy products and Parkinson's disease. 7 Both iron preparations and beef, which has a high iron load, were associated with a quick progression in this study, which corresponds to the assumption that iron due to its oxidative nature Symptom progression drives.

While Coenzyme Q10 (COQ10) was promising early in the Parkinson's disease, newer randomized controlled studies showed no benefits. 9 It is interesting that the connection between delayed progression and Coenzyme Q10 was no longer statistically significant in this study. The author postulates that COQ10, an expensive nutritional supplement, could be a replacement for a high income status that was associated with a delayed progression, possibly due to better access to health care.

This study has some excellent strengths. The researchers adjusted all the results of age, gender, years since the diagnosis and income level, and the results give us the first indications of the effect of nutrition and nutritional supplements on Parkinson's disease. Of course there are also restrictions on this study. Conclusion from the study design are limited as a cross -sectional analysis. This study is a longitudinal study and this publication is temporary and does not claim to be complete. The researchers also not corrected the p values ​​for multiple comparisons, so that it is possible that some statistically significant associations are wrong.

In summary, this study presents some interesting preliminary results in terms of nutrition and nutritional supplements for Parkinson's disease. This is an important first step that will follow further work by the study authors and other researchers.

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