Do you suffer from depression or anxiety? You may have pyroluria
Pyroluria is a genetic abnormality in hemoglobin synthesis that affects up to 10% of the population (although most people don't know they have it). It usually causes mental disorders such as depression and anxiety and in severe cases can cause bipolar and schizophrenia if left untreated. Memory problems, insomnia, learning problems, low stress tolerance, and irritability may be additional symptoms, as well as a number of other signs and symptoms (see below). It can be triggered by prolonged stress or a traumatic event, although often there are no known triggers and symptoms often begin in the teens or early 20s. People with this...

Do you suffer from depression or anxiety? You may have pyroluria
Pyroluria is a genetic abnormality in hemoglobin synthesis that affects up to 10% of the population (although most people don't know they have it). It usually causes mental disorders such as depression and anxiety and in severe cases can cause bipolar and schizophrenia if left untreated. Memory problems, insomnia, learning problems, low stress tolerance, and irritability may be additional symptoms, as well as a number of other signs and symptoms (see below). It can be triggered by prolonged stress or a traumatic event, although often there are no known triggers and symptoms often begin in the teens or early 20s.
People with this biochemical imbalance have high levels of pyrrole in their bodies, a neurotoxic substance that affects the nervous system and brain and, at elevated levels, can cause mental illness. Pyrroles are a byproduct that occurs during red blood cell (RBC) production and are broken down and effectively eliminated in non-pyroluria patients. However, if someone has undiagnosed and untreated pyroluria, the pyrroles are not broken down and eliminated efficiently enough. They accumulate in the body and bind to certain essential nutrients such as vitamin B6, zinc, magnesium, manganese, biotin and others, leaving the body depleted of these nutrients.
Treating the condition with proper supplementation, such as a coenzymated form of B6 and zinc, as well as manganese, biotin, magnesium, niacin, omega-6 fatty acids (particularly arachidonic acid), vitamin C, and other nutrients, reduces toxic pyrrole levels and increases these essential nutrients. Supplementing with a coenzymated B6 also allows the body to produce serotonin, which it cannot achieve without optimal B6 levels. If OCD, bipolar or schizophrenia have already developed, additional supplementation may be required, such as NAC for OCD and bipolar disorder or vitamin B3 for schizophrenia, therefore an individual approach is required. Treatment with the right supplement and diet usually results in complete resolution of symptoms for patients with pyroluria as long as they take the supplements and eat an appropriate, healthy diet.
The following signs and symptoms may occur in people suffering from pyroluria. If you have at least 8 of these symptoms, consult a naturopath or doctor for testing:
Fear; Nervousness; strong internal tension
depression
Poor ability to deal with stress
Emotional instability
Mood swings or temper outbursts
Panic attacks
addictive personality; Drug abuse
Cravings for high-carb and high-sugar foods
neuroses
Obsessive compulsive disorder (OCD)
Episodic anger/temper outbursts/explosive temper
Histrionic (dramatic)
Argumentative / enjoys an argument
insomnia
Fatigue
Pessimistic thought patterns
Digestive problems, e.g. B. Abdominal tenderness; constipation, IBS, etc.
Glucose intolerance/hypoglycemia
alcoholism
Little or no dream recall
White spots on fingernails
Frequent infections with colds; Poor immune function
Poor appetite in the morning and a tendency to skip breakfast
Frequent unexplained nausea
Much higher abilities and alertness in the evening compared to the morning
Increased sensitivity to bright lights, loud noises, smells and touch.
Joint pain, especially knees/legs; Restless Legs Syndrome; creaking knees
Food allergies or intolerances/environmental allergies/sensitivities
Sensitivity to medications
learning difficulties (e.g. dyslexia, dyscalculia, etc.); Auditory processing disorder
Behavioral problems in children and adolescents such as oppositional defiant disorder
Antisocial behavior
ADHD
Disorganization
Poor short-term memory
Skin problems such as acne, eczema, psoriasis and dry skin
Significant growth after age 16
Delayed onset of puberty
Crowded teeth and poor tooth enamel; receded gums/gum disease; sensitive teeth
Cold hands and feet even in summer
Sweet, fruity breath and body odor
Abnormal body fat distribution (diaphragmatic tendency)
Stretch marks
Coarse eyebrows
Growth disorders
Tremble
Motion sickness
Irregular menstruation
migraine
Impotence in men
Tics
Drooping eyelids
Pale skin + poor tanning + slight burning in the sun
Likes routine (especially as a child)
Emotional withdrawal
Social withdrawal
Gluten intolerance or celiac disease
Eosinophilia (increased levels of eosinophils – a type of white blood cell)
Anemia/low iron levels
Increased copper levels
Increased heavy metal levels
IN SEVERE CASES:
Emotional lability (emotional overreaction, such as uncontrollable laughing or crying, or inappropriate emotions, such as excessive anger or irritability or laughing when something is sad), especially when you are stressed or tired.
Impaired perception; Loss of reality
hallucinations; Delusions
paranoia
Suicidal tendencies
Autism, Asperger's
Bipolar (manic depression)
schizophrenia
Down syndrome
Epilepsy; Seizures
Tourett syndrome
Acute intermittent porphyria
Latent Acute Intermittent Porphyria (Note: Porphyria is a group of rare genetic disorders involved in heme production)
Dissociative Identity Disorder (DID) – commonly known as multiple personality disorder
If you suffer from depression, anxiety, or another mental health disorder and have 8 or more of the signs or symptoms in the list above, contact a naturopath or doctor for testing and advice on the best treatments for pyroluria. The test is a non-invasive urine test. If the test shows that you have pyroluria, your doctor will make treatment recommendations based on your individual needs.
Please share this article in case it may help other people who unknowingly have this condition and suffer unnecessarily with simple treatments.