Healing for HIV infection: Another HIV patient healed with stem cell transplantation

Veröffentlicht:

Von:

Yes, an HIV infection can be healed. Three HIV-infected people have been healed so far. In all of these cases, a hematopoetic stem cell transplantation was carried out, which is used in the treatment of severe blood cancer. Previously, two HIV patients had already been healed by this medical intervention. The third case was published in Nature Medicine this week. It was found by an international group of doctors and researchers from Germany, the Netherlands, France, Spain and the United States. It was also the first time that the successful healing process of the HIV patient was virologically and immunologically characterized over a period of 10 years, the researchers said. Meet …
(Symbolbild/natur.wiki)

Yes, an HIV infection can be healed. Three HIV-infected people have been healed so far. In all of these cases, a hematopoetic stem cell transplantation was carried out, which is used in the treatment of severe blood cancer. Previously, two HIV patients had already been healed by this medical intervention. The third case was published in Nature Medicine this week. It was found by an international group of doctors and researchers from Germany, the Netherlands, France, Spain and the United States.

It was also the first time that the successful healing process of the HIV patient was characterized virologically and immunologically over a period of 10 years, according to the researchers.

meet the third patient who is completely healed by HIV

A 53-year-old man from Düsseldorf is the third person in the world who was completely healed by the human immune deficiency virus (HIV). He was treated in the Düsseldorf University Hospital for his HIV infection and received a stem cell transplant due to a blood cancer.

The first two HIV patients who have been healed in the past were called "Berlin" and "London". Like these first two cases, the Düsseldorf patient received stem cells from a healthy donor. The genome of the donor contains a mutation in the gene for the HIV-1 CO receptor CCR5, which makes it impossible for most human immune deficiency viruses to penetrate its main cell cells into human CD4+ T lymphocytes, according to a report by Science Daily.

After the stem cell transplantation, the patient was monitored virologically and immunologically for almost 10 years. The researchers analyzed his blood and tissue samples shortly after the transplant and during the entire study period with a number of sensitive techniques, although neither replicating viruses nor antibodies or reactive immune cells against HIV could be detected.

The patient had dropped the antiviral therapy against HIV more than four years ago. Ten years after the stem cell transplantation and four years after the end of anti-HIV therapy, the Düsseldorf patient was explained by the international research group for healed.