研究人员曾经收到没有连贯结构的DNA片段，因此DNA降解并遭受化学损害，因此研究人员的遗传学家Erez Lieberman Aiden说。他说，重建3D基因组几乎是不可能的：哺乳动物的基因组比典型的古代DNA片段大3000万倍。
惊人的发现
在这一假设的挑战中，利伯曼·艾登（Lieberman Aiden）和他的同事们开始了九年来寻找良好的古董排练，并最终发现了52,000 -year -ol -old wold羊毛皮肤样品中几乎完整的染色体（ mammmammuthus primigenius primigenius ），来自Sibermian permamian permam。贝勒医学院的遗传学家Mitachor CynthiaPérezEstrada研究说，这一发现是“令人叹为观止的”。
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