CBD and Phytocannabinoids do not inhibit the production of endocannabinoids
CBD and Phytocannabinoids do not inhibit the production of endocannabinoids
CBD and Phytocannabinoids do not inhibit the production of endocannabinoids
by Prof. Gene Bruno, MS, MHS, RH (AHG)
Huntington College for Health Sciences
Lately I have spent a lot of time to study research on the effect of CBD and Phytocannabinoids on the Endocannabinoid system. When I discussed this research with colleagues, I was interested to find out that some people were concerned that supplementation with CBD/Phytocannabinoids could impair the body's own production of endocannabinoids-similar to testosterone injections, the body is less producing its own testosterone .
I am happy to be able to tell you that this concern is unfounded. In contrast to testosterone in injections, which essentially has the same chemical structure as the body's testosterone, phytocannabinoids do not have the same chemical structure as the endocannabinoids produced in the body. It works in this way. n-arachidonyllethanolamide (AEA) and SN-2-Arachidonoylglycerol (2-AG) are the two endocannabinoids produced in the body that bind to receptors within the endocannabinoid system (ECS). After that, an enzyme in the body called fatty acid hydrolase (FAAH) AEA and 2-AG-which means that there are now less endocannabinoids to perform their task. In combination with other factors (e.g. inadequate consumption of phytocannabinoids containing food such as broccoli, cabbage, carrots, parsley, 1 sunflower seeds and peas), this can lead to a suboptimal function of the ECB system, also known as "ECB deficiency syndrome". The condition can be associated with migraines, fibromyalgia, irritable bowel syndrome, mental disorders and other diseases. 3 However, if significant amounts of phytocannabinoids such as CBD are consumed, the FAAH is used to dismantle it instead of reducing the endocannabinoids. This helps to maintain a healthy endocannabinoid level and to extend their effect. 4 This series of Phytocannabinoids has a value as an entourage connections to increase the effect of endocannabinoids by inhibiting their hydrolysis through substrate competition and extending their effect. The use of phytocannabinoids clearly does not mean that the body produces less of its own endocannabinoids - on the contrary. references: 1. Gertsch J, Pertwee RG, Di Marzo V. Phytocannabinoids beyond the cannabis plant - is they? br. J. Pharmacol. June 2010; 160 (3): 523-9. Professor Gene Bruno, MS, MHS, The provost for Huntington College for Health Sciences, is a nutritionist, herbalist, author and educator. For more than 37 years, he has trained and trained natural product retailers and medical staff, researched and formulated natural products for dozens of food supplements and formulated articles on nutrition, herbal medicine, nutrotquional agents and integrative health issues for trade and consumers. It can be reached at gbruno@hchs.edu. Read original items in English.